Use of acetyl D-carnitine in the therapeutic treatment of glauco

Details Use of acetyl D-carnitine in the therapeutic treatment of glauco Use of acetyl D-carnitine in the therapeutic treatment of glauco

1989-11-28

1992-09-08

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514913, A61K 3122

Patent

active

051458713

ABSTRACT:
The use is described of acetyl D-carnitine and its pharmacologically acceptable salts in the therapeutic treatment of glaucoma. The medicament may be administered orally or parenterally or be applied as a collyrium containing approximately 1-10% w/v of acetyl D-carnitine.

REFERENCES:
patent: 4724230 (1988-02-01), Cone, Jr.
Int. J. Tiss. Reac., vol. 6, No. 2, 1984, Bioscience Ediprint Inc., Z. Farinella et al.: "Effects of carnitine and acetylcarnitine isomers on mitochondrial respiration", pp. 141-143, see summary Relevant To Claim No. 1,3-8.
Dialog Information Services, File 5, (Biosis), Accession No.: 0019195970, L. Scorolli et al.: "Evaluation of effects of L acetylcarnitine on some functional parameters in a senile glaucomatous patient", & Ann Ottalmol Clin Ocul 114 (9),1988, 927-934, see the whole abstract. Relevant To Claim NO. 1,3-8.
Journal of Pharmaceutical Sciences, vol. 69, No. 9, Sep. 1980, American Pharmaceutical Association, K. W. Reed et al.: "Acetylcarnitine and cholinergic receptors", pp. 1065-1068, see p. 1066: Experimental Relevant To Claim No. 1,3-8.
The Merck Manual of Diagnosis and Therapy, 1987, 15th edition, edited by R. Berkow et al., Merck Sharp & Dohme Research Laboratories, (Rahway, N.J. U.S.), pp. 2234-2240, chapter 224: "Glaucoma" see pp. 2236-2237 Relevant To Claim No. 1,3-8.

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