Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones

Details Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones

1981-06-15

1982-12-28

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26358

Patent

active

043663192

ABSTRACT:
5-PY-benzoxazol-2(3H)-ones, cardiotonic agents, are prepared by reacting 2-amino-4-PY-phenol with a carbonylating agent, e.g., carbonyldiimidazole, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents. 5-PY-benzoxazol-2(3H)-ones or pharmaceutically-acceptable acid-addition or cationic salts thereof are disclosed as active components in cardiotonic compositions for increasing cardiac contractility and in the method for increasing cardiac contractility in a patient requiring such treatment.

REFERENCES:
Chem. Abstract 56:15516g.
Chem. Abstract 90:72191u.
Derwent Abstract 79163A/44, *J5 3111-062 on Japanese Patent 024432 (9-28-78).
Coates et al. [J. Chem. Soc. 1943, 406].
Heilbron et al. [J. Chem. Soc. 1940, 1279].

Affiliated with

Also associated with

Rating

Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1338199