Preparation and uses of alpha-glycosyl rutin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 74, 435 96, 435 97, 536 8, 536124, 426541, 426658, 514 26, 514844, 514777, 252397, 2523635, C12P 1914, C12P 1920, C12P 1918, C12P 1944

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051457814

ABSTRACT:
Alpha-glycosyl rutin is formed at a high concentration by allowing a saccharide-transferring enzyme to act on a high-rutin content liquid in suspension or solution to effect saccharide-transfer reaction. The resultant alpha-glycosyl rutin is easily recovered from the reaction mixture by allowing it to contact with a synthetic macroreticular resin. Alpha-glycosyl rutin is superior in water-solubility, resistance to light and stability to intact rutin, as well as having the physiological activities as intact rutin has. Thus, alpha-glycosyl rutin is favorably usable as a yellow coloring agent, antioxidant, stabilizer, fading-preventing agent, quality-improving agent, preventive, remedy, uv-absorbent and deterioration-preventing agent in foods, beverages, tobaccos, cigarettes, feeds, pet foods, pharmaceuticals for susceptive diseases, cosmetics including skin-refining agent and skin-whitening agent, and plastics, in addition to the use in vitamin P-enriching agents.

REFERENCES:
patent: 4338398 (1982-07-01), Yoneyama
patent: 4636394 (1987-01-01), Hsu
patent: 4755504 (1988-07-01), Liu
patent: 4774229 (1988-09-01), Jordan
patent: 4837006 (1989-06-01), Rosenbaum et al.
Yamasaki et al., Biological Abstracts, vol. 66 (11), Dec. 1, 1978, #67094.
Majoie, Chemical Abstracts, vol. 95, Jul. 20, 1981, #25550d.
"Water Soluble Derivatives of Vitamin P," Japanese Patents Report, sec. CH, vol. 79, No. 42, Nov. 16, 1979, p. J7-B (Japanese Patent J79-032073).
"Preparation of Glycosyl Vitamins," Chemical Abstracts, vol. 96, No. 24, Jun. 14, 1982, p. 379, Abstract No. 205 400j (Japanese Patent J81-156,299).
"Flavonoids as Drugs", Chemical Abstracts, vol. 97, No. 7, Aug. 16, 1982, p. 518, Abstract No. 54 317e.

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