Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-12-23
2000-07-25
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5462727, 5462741, 5462744, 5462747, 5462751, 546256, 544333, 544405, 514333, 514256, 514255, C07D40106, A61K 3144
Patent
active
060937378
ABSTRACT:
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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Anthony Neville J.
Gomez Robert P.
Tran Lekhanh O.
Young Steven D.
Daniel Mark R.
Fan Jane
Merck & Co. , Inc.
Muthard David A.
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