Amylase variants

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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510226, 510236, 510530, 510320, 510392, C12N 928

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active

060935626

ABSTRACT:
The present invention relates to variants of a parent .alpha.-amylase, which parent .alpha.-amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, and SEQ ID No. 7, respectively; or (ii) displays at least 80% homology with one or more of these amino acid sequences; and/or displays immunological cross-reactivity with an antibody raised against an .alpha.-amylase having one of these amino acid sequences; and/or is encoded by a DNA sequence which hybridizes with the same probe as a DNA sequence encoding an .alpha.-amylase having one of these amino acid sequences; in which variant:

REFERENCES:
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Estell, D.A., et al., The Jour. Biol. Chem., vol. 260, No. 11, pp. 6518-6521 (1985).
Abstract--Dialog, File 351, Derwent WPI, Dialog Accession No. 007176688 (1987).
Suzuki, Y., et al., The Jour. of Biol. Chem., vol. 264, No. 32, pp. 18933-18938 (1989).
Chemical Abstracts, vol. 112, No. 15, The Abstract No. 135178r, p. 347 (1990).
Chemical Abstracts, vol. 108, No. 11, The Abstract No. 90927h, p. 325 (1988).
Chemical Abstracts, vol. 112, No. 19, The Abstract No. 174785f, p. 350 (1990).

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