Antiestrogens and their use in treatment of menopause and osteop

Details Antiestrogens and their use in treatment of menopause and osteop Antiestrogens and their use in treatment of menopause and osteop

1988-01-12

1990-01-16

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514317, 514408, 514569, 514649, 514731, 514874, 514899, A61K 31535, A61K 31445, A61K 3140, A61K 3119

Patent

active

048943738

ABSTRACT:
Disclosed is a method for treating menopausal symptoms and treating and preventing osteoporosis, wherein a true antiestrogen is administered and estrogen is not. This treatment is effective for female osteoporosis and can also be used to treat male osteoporosis. Examples of true antiestrogens are clomiphene, and its isomers, citrates and derivatives, as well as several other compounds which appear in the specification.

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T. Hashimoto et al.: "Effect of Clomiphene Citrate on Basal and LHR-Induced Gonadotropin Secretion in Postmenopausal Women", *Whole Article*.
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