Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Patent
1987-07-01
1990-01-16
Benson, Robert
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
436547, 436800, 436805, 436808, 530390, 530802, 549223, 549225, G01N 33533
Patent
active
048943487
ABSTRACT:
A method for conducting assays for an analyte, usually in a biological sample, utilizes reagents which contain biological ligands linked to fluorescein or a derivative of fluorescein through a linkage to the fluorescein nucleus selected from acetamido and thioacetamido. In these reagents, the fluorescence efficiency is improved over that obtained in the commonly used FITC-labeled reagents.
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Franzen et al., (1980) Biochemistry 19:6080-6089.
Ogamo et al., (1982) Carbohydrate Research 105:69-85.
Blatt et al., (1986) Biochim. Biophys. Acta 857:85-94.
Nguyen Phuc H.
Rowley Gerald L.
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