Method for the early diagnosis of cancer

Details Method for the early diagnosis of cancer Method for the early diagnosis of cancer

1993-03-26

1994-09-06

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 4, 435 36, 435 38, 435848, 435885, 436 63, 436 64, C12Q 106, G01N 3348

Patent

active

053447620

ABSTRACT:
In a method for early diagnosis of human cancer, a human fecal sample of bacteria (Escherichia coli and/or Streptococcus faecalis), is incubated in vitro with a standard culture of a known number of cancer cells, for a period of time sufficient to enable the extent of interaction between the bacteria and the standard culture of cancer cells to be determined; the number of the interacted and/or non-interacted cancer cells present at the end of the period is determined and is utilized for the diagnosis based on the calculation of a tumor cell necrosis index (TCNI). The extent of interaction referred to may be calibrated against analogous interaction using a control preparation of bacteria, e.g. Escherichia coli A.T.C.C. 55373, 55374 and/or 55375, and/or Streptococcus faecalis A.T.C.C. 55376.

REFERENCES:
patent: 4582787 (1986-04-01), Frankel
Acevedo et al, Journal of General Microbiology, vol. 133, pp. 783-791, 1987.
Garbitelli et al, JAMA, vol.. 247, No. 13, p. 1812, Apr. 2, 1982.
Oleynik, S. F. and Panchishina, M. V., "About Coliflora and Cancerolycity and Carcinogenicity of the Intestine", Vrachebnoye-delo, 1968, 5:13-17.

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