Benzopyranol derivatives

Details Benzopyranol derivatives Benzopyranol derivatives

1999-03-02

1999-11-16

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549433, C07D31770, C07D49306

Patent

active

059861142

ABSTRACT:
The invention relates to benzopyranol derivatives which are intermediates in a process for stereoselectively forming N-substituted dihydro-2,3 benzodiazopines which are useful as AMPA receptor antagonists. The process includes an opening reduction step which sets the stereochemistry of the intermediates and the final compounds to the desired enantiomer. The reduction step may be carried out by an enzymatic reduction.

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