Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-06-16
1999-11-16
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514212, 5142335, 514320, 514422, 514443, 514470, A61K 31445
Patent
active
059858982
ABSTRACT:
A method for alleviating the symptoms of post-menopausal syndrome comprising administering to a woman in need thereof an effective amount of a compound of formula I ##STR1## wherein R.sup.1a is --H or --OR.sup.7a in which R.sup.7a is --H or a hydroxy protecting group;
REFERENCES:
patent: 3293263 (1966-12-01), Lednicer
patent: 3320271 (1967-05-01), Lednicer
patent: 3394125 (1968-07-01), Crenshaw
patent: 3413305 (1968-11-01), Crenshaw
patent: 3689672 (1972-09-01), Pesterfield
patent: 3729443 (1973-04-01), Peterli et al.
patent: 3862232 (1975-01-01), Lednicer
patent: 3947470 (1976-03-01), Brenner et al.
patent: 4001426 (1977-01-01), Brenner et al.
patent: 4117128 (1978-09-01), Brenner
patent: 4133814 (1979-01-01), Jones et al.
patent: 4136197 (1979-01-01), Hubner et al.
patent: 4191776 (1980-03-01), Nickl et al.
patent: 4230862 (1980-10-01), Suarez et al.
patent: 4304940 (1981-12-01), Wedemeyer et al.
patent: 4418068 (1983-11-01), Jones
patent: 4910212 (1990-03-01), Boyle et al.
patent: 5013761 (1991-05-01), Beedle et al.
patent: 5223510 (1993-06-01), Gubin et al.
patent: 5254568 (1993-10-01), Kapil et al.
patent: 5384332 (1995-01-01), Fontana
patent: 5470854 (1995-11-01), von Angerer et al.
patent: 5484798 (1996-01-01), Bryant et al.
patent: 5488058 (1996-01-01), Palkowitz
patent: 5492922 (1996-02-01), Palkowitz
patent: 5510357 (1996-04-01), Palkowitz
patent: 5510358 (1996-04-01), Palkowitz
patent: 5510498 (1996-04-01), Palkowitz
patent: 5574190 (1996-11-01), Palkowitz
patent: 5723474 (1998-03-01), Palkowitz
Oparil "Hypertensio is postmenopausal women:pathophysiology and management" Current opinion . . . , EMBASE No. 95283951, 1995.
Insua et al. "Postmenopause, plasma lipoproteins and hormone replacement therapy" Medline 94260928, 1993.
Schwandt "Triglyceride rich lipoproteins and atherosclerosis" Medline 91146429, 1991.
Crenshaw, R. R., et al., J. Med. Chem., 14(12): 1185-1190 (1971).
Durani, N., et al., Indian J. Chem., 22B: 489-490 (1983).
Jones, C. D., et al., J. Med. Chem., 35: 931-938 (1992).
Lednicer, D., et al., J. Med. Chem., 8: 52-57 (1964).
Madesclaire, M., Tetrahedran, 42(20): 5459-5495 (1986).
Trost, B. M., et al., Tetrahedren Letters, 22(14): 1287-1290 (1981).
Drabowicz, J., et al., Synthetic Communications, 11(12): 1025-1030 (1981).
Kramer, J. B., et al., 34.sup.th National Organic Symposium, Williamsburg, VA, (Jun. 11-15, 1995).
Wyngaarden, et al., Cecil Textbook of Medicine, 16: 1271 (1983).
Kaiser, G. V., et al., J. Org. Chem., 35(7): 2430-2433 (1970).
Venier, C. G., et al., J. Org. Chem., 47: 3773-3774 (1982).
Jones, et al., J. Med. Chem., 27: 1057-1066 (1984).
El Amoudi, et al., Chem. Abstracts, 95: 149807 (1981).
Boudreaux William R.
Chang Ceila
Eli Lilly and Company
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