High-throughput screening assays for modulators of primase activ

Details High-throughput screening assays for modulators of primase activ High-throughput screening assays for modulators of primase activ

1998-03-31

2000-03-28

Fredman, Jeffrey

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 5, 435 912, 435 9121, 435 915, 536 231, 536 243, 536 2431, 536 2432, 536 2433, 530350, C12Q 168, C12P 1934, C07H 2102, C07H 2104

Patent

active

060430389

ABSTRACT:
This invention provides novel assays for primase activity and for identifying modulators of primase activity. The assays include both solid-phase and liquid-phase methods that are amenable to high throughput screening methods. The assays of the invention are readily adaptable to numerous types of primase, and are capable of identifying novel classes of primase activity modulators.

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