Process for producing optically active azetidine-2-carboxylic ac

Details Process for producing optically active azetidine-2-carboxylic ac Process for producing optically active azetidine-2-carboxylic ac

1997-09-05

1999-03-09

Powers, Fiona T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20504

Patent

active

058802916

ABSTRACT:
The present invention provides a process for preparing optically active azetidine-2-carboxylic acids using readily available reagents of relatively low price in the industry. Thus, there is provided optically active azetidine-2-carboxylic acid, and a process for producing the same by subjecting optically active N-(alkylbenzyl)azetidine-2-carboxylic acid represented by the formula (1): ##STR1## to hydrogenolysis in the presence of a catalyst.

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R. M. Rodebaugh et al., A Facile New Synthesis of DL-Azetidine-2-carboxylic Acid (1a), . J. Heterocyclic Chem, vol. 6, pp. 435-437, 1969.
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