Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Light application
Patent
1998-05-04
2000-03-28
Dvorak, Linda C. M.
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Light application
607 88, 607 92, 604 20, A61N 500
Patent
active
060426039
ABSTRACT:
An apparatus for the treatment of a particular volume of plant or animal tissue by treating the plant or animal tissue with at least one photo-active molecular agent, wherein the particular volume of the plant or animal tissue retains at least a portion of the at least one photo-active molecular agent, and then treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of at least one of the at least one photo-active molecular agent retained in the particular volume of the plant or animal tissue, wherein the at least one photo-active molecular agent becomes active in the particular volume of the plant or animal tissue.
REFERENCES:
patent: 4822335 (1989-04-01), Kawai et al.
patent: 4925736 (1990-05-01), Shikowitz
patent: 4973848 (1990-11-01), Kolobanov et al.
patent: 5034613 (1991-07-01), Denk et al.
patent: 5053006 (1991-10-01), Watson
patent: 5231984 (1993-08-01), Santana-Blank
patent: 5558666 (1996-09-01), Dewey et al.
patent: 5576013 (1996-11-01), Williams et al.
patent: 5586981 (1996-12-01), Hu
patent: 5643334 (1997-07-01), Eckhouse et al.
J.W. Tessman, et al., "Photochemistry of Furan-Side 8-Methoxypsoralen-Tymidine Monoadduct Inside the DNA Helix, Conversion to Diadduct and to Pyrone-Side Monoadduct," Biochemistry, 24 *1985) 1669-1676.
J.C. Kennedy, et al., "Photodynamic Therapy with Endogenous Protoporphyrin IX: Basic Principles and Present Clinical Experience," J. of Photochemistry and Photobiology, B: Biology, 6 (1990) 143-148.
K. Teuchner, et al., "Spectroscopic Properties of Potential Sensitizers for New Photodynamic Therapy Start Mechanisms via Two-Step Excited Electronic States," Photochemistry and Photobiology 57 (1993) 465-471.
A.R. Young, "Photocarcinogenicity of Psoralens Used in PUVA Treatment: Present Status in Mouse and Man," J. of Photochemistry and Photobiology, B. Biology, 6 (1990) 237-247.
M.J. Wirth, et al., "Two-Photon Excited Molecular Fluorescence in Optically Dense Media," Analytical Chemistry, 49 (1977) 2054-2057.
M.J. Sepaniak, et al., "Laser Two-Photon Excited Molecular Fluorescence Detection for Hihgh Pressure Liquid Chromatography," Analytical Chemistry, 49 (1977) 1554-1556.
M.J. Sepaniak, et al., "High-Performance Liquid Chromatographic Studies of Coal Liquids by Laser-Based Detectors," J. Of Chromatography, 211 (1981) 95-102.
W.D. Pfeffer, et al., "Laser Two-Photon Excited Fluorescence Detector for Microbore Liquid Chromatography," Analytical Chemistry, 58 (1986) 2103-2105.
M.J. Wirth, et al., "Very High Detectability in Two-Photon Spectroscopy," Analytical Chemistry, 62 (1990) 2103-2105.
J.E. Hearst, et al., "The Reaction of the Psoralens with Deoxyribonucleic Acid", Quarterly Review of Biophysics, 17 (1984) 1-44.
Fisher, A.M.R. et al. "Clinical and Preclinical Photodynamic Therapy" Laser Surg. Med. 1 7, 2-31 (1995).
Cheong, W-F. et al., "A Review of the Optical Properties of Biological Tissues" IEEE 5. Quant. Election 2 6, 2166-2185 (1990).
Dougherty, T.J. et al., "Photoradiation Therapy II Cure of Animal Tumors With Hematoporphyrin and Light" J. Nat'l Cancer-Inst. 5 5, 115-120 (1975).
Gomer, C.J. et al. (1989) Properties and applications of photodynamic therapy. Rad. Res. 1 2 0, 1-18.
Kessel, D. et al., (1991) Photophysical and photobiological properties of diporphyrin ethers. Photochem. Photobiol. 5 3, 469-474.
Dolphin, D., (1994) 1993 Syntex award lecture, photomedicine and photodynamic therapy. Can. J. Chem. 7 2, 1005-1013.
Katsumi, T.A., et al., (1996) Photodynamic therapy with a diode laser for implanted fibrosarcoma in mice Employing mono-L-aspartyl chlorin E6. Photochem. Photobiol. 6 4, 671-675.
Gopert-Mayer, M., (1931) Elementary process with two quantum jumps. Ann. Physik 9, 273-294.
Kaiser, W. and C.G.B. Garrett, (1961) Two photon excitation in CaF.sub.2 :Eu.sup.2+. Phys. Rev. Lett. 7, 229-231.
Monson, P.R. and W.M. McClain (1970) Polarization dependence of the two-photon absorption of tumbling molecules with application of liquid 1-choronaphthalene and benzene. J. Chem. Phys. 5 3, 29-37.
Wilson, B.C. and M.S. Patterson, (1986) The physics of photodynamic therapy. Phys. Med. Biol. 3 1, 327-360.
Draumer, N.H., et al., (1997) Femtosecond dynamics of excited-state evolution in [Ru(bpy).sub.3 ].sup.2+. Science 2 7 5, 54-57.
Swofford, R.L. and W.M. McClaim, (1975) The effect of saptial and temporal laser beam characteristics on two-photon absorption. Chem. Phys. Lett. 3 4, 455-459.
Hammer, D.X. et al., (1996) Experimental investigation of ultrashort pulse laser-induced breakdown thresholds in aqueous media. Ieee J. Quant. Electron. 3 2, 670-678.
Andreoni, A., et al., (1982) Two-step lazer activation of hematoporphyrin derivative. Chem. Phys. Lett. 8 8, 37-39.
Shea, C.R., et al., (1990) Mechanistic investigation of doxycyckine photosensitization by picosecond-pulsed and continuous wave laser irradiation of cells in culture. J. Biol. Chem. 2 6 5, 5977-5982.
Inaba, H., et al., (1985) Nd:YAG laser-induced hematoporphyrin visible flourescence and two-photon-excited photochemical effect on malignant tumor cells. J. Opt. Soc. Am. A:Opt. Inage Science 2, P72 (mtg abstr).
Mashiko, S., et al., (1986) Two-photon excited visible flourescence of hematoporphyrin and phiophorbide a and in vitro experiments of the photodynamic . . . J. Opt. Soc. Am. B:Opt. Phys 3, P72-P73 (mtg. abstr).
Yamashita, Y. et al., (1991) Photodynamic therapy using pheophorbide-a and Q-switched Nd:YAG laser on implanted human hepatocellular carcinoma. Gast. Jap. 2 6, 623-627.
Fugishima, I., et al., (1991) Photodynamic therapy using phophorbide a and ND:YAG laser. Neurol. Med. Chir. (Tokyo) 3 1, 257-263.
Mashiko, S., et al., (1985) Basic study on photochemical effect of pheophorbide-a irradiated by Nd:YAG laser light. Nippon Laser Igakukaishi 6,113-116.
Steil, H., et al., (1993) Photophysical properties of the photosensitizer phophorbide a studied at high photon flux densities. J. Photochem. Photobiol. B: Biology 1 7, 181-186.
Bodaness, R.S. and D.S. King (1985) The two-photon induced flourescence of the tumor localizing photo-sensitizer hematoporphyrin derivative via 1064 nm . . . Biochem. Biophys. Res. Comm. 1 2 6, 346-351.
Bodaness, R.S., et al., (1986) Two-photon laser-induced fluorescence of the tumor-localizing photosensitive hematoporphyrin derivative. J. Biol. Chem. 2 6 1, 12098-12101.
Lenz, P., (1995) In vivo excitation of photosensitizers by infrared light. Photochem. Photobiol. 6 2, 333-338.
Patrice, T., et al., (1983) Neodymium-yttrium aluminum garnet laser destruction of nonsensitized and hematoporphyrin derivative-sensitized tumors. Canc. Res. 4 3, 2876-2879.
Marchesini, R., et al., (1986) A study on the possible involvement of nonlinear mechanism of light absorption by HpD with Nd:YAG laser. Lasers Surg. Med. 6, 323-327.
Oh, D.H., et al., (1997) Two-photon excitation of 4'-hydroxymethyl-4,5', 8-trimethylpsoralen. Photochem. Photobiol. 6 5, 91-95.
Prasad, P.N. and G.S. He, (1996) Multiphoton resonant nonlinear-optical processes in organic molecules ACS Symposium Series 6 2 8, 225-236.
Dagani, R., (1996) Two photons shine in 3-D data storage. Chem Eng. News, Sep. 23, 1996, 68-70.
Lytle, F.E., (1981) Laser fundamentals. In Lasers in Chemical Analysis (Ed.: G.M. Hieftje, et al.) 5-6. The Humana Press, New Jersey.
Song, P.S. and K.J. Tapley, Jr. (1979) Photochemistry and photobiology of psoralens. Photochem. Photobiol. 2 9, 1177-1197.
Hearst, J.E. et al. (1984) The areaction of a psoralens with deoxyribonucleic acid. Q. Rev. Biophys. 1 7. 1-44.
Cimino, G.D., et al., (1985) Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry. Ann. Rev. Biochem. 5 4, 1151-1193.
Fisher, W.G., et al., (1997) Two-photon spectroscopy and photochemistry of tris(2,2'-bipyridine)-ruthenium(II). J. Phys. Chem. (in press).
Moscatelli, F.A., (1985) A simple conceptual model for two-photon absorption. Am. J. Phys. 5 4, 52-54.
Fisher, W.G., et al., (1997) The titanium:sapphire laser as an excitation source in two-photon spectroscopy. Appl. Spctrosc. 5 1
Dees H. Craig
Fisher Walter G.
Wachter Eric A.
Dvorak Linda C. M.
Photogen, Inc.
Yarnell Bryan K.
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