Keto amide derivatives useful as farnesyl protein transferase in

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514290, 544361, 546 93, C07D40104, C07D40112, A61K 3144, A61K 31495

Patent

active

059256397

ABSTRACT:
Compounds of the following formula useful for inhibiting Ras function and therefore inhibiting or treating the abnormal growth of cells are disclosed: ##STR1## or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof, wherein:

REFERENCES:
patent: 5151423 (1992-09-01), Piwinski et al.
patent: 5684013 (1997-11-01), Afonso et al.
patent: 5696121 (1997-12-01), Bishop et al.
patent: 5714609 (1998-02-01), Doll et al.
patent: 5719148 (1998-02-01), Bishop et al.
Njoroge et al, Bioorganic & Med. Chem. Let., 6 (1996), pp. 2977-2982.
Njoroge et al, Bioorganic & Med. Chem. Let., 5 (1997), pp. 101-113.
Buss et al, Chem. and Bio., 118 (1995), pp. 787-791.
Bishop et al, J. Biol. Chem., 270 (1995), pp. 30611-30618.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Keto amide derivatives useful as farnesyl protein transferase in does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Keto amide derivatives useful as farnesyl protein transferase in, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Keto amide derivatives useful as farnesyl protein transferase in will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1322050

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.