Diastereocontrolled synthesis of 2-amino alcohols

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

549 60, 549 68, 549 78, 549214, 549472, 549480, 556423, 564250, 564251, C07D32700, C07D33336, C07C10912, C07C10916

Patent

active

047436948

ABSTRACT:
The addition of organolithium to dimethylhydrazones of certain ethers of a-hydroxyaldehydes results in the synthesis of threo- or erythro- intermediates readily convertible to threo- or erythro-2-amino alcohols.

REFERENCES:
patent: 3882124 (1975-05-01), Kirchlechner et al.
patent: 3897453 (1975-07-01), Gante et al.
patent: 3943132 (1976-03-01), Schirmann et al.
patent: 3948949 (1976-04-01), Gante et al.
patent: 4644011 (1987-02-01), Ballenegger et al.
J. Org. Chem, 50 3752-3757 (1985), Roush, W. R.
J. Am. Chem. Soc., 107, 1797-8 (1985), Hirama et al.
J. Am. Chem. Soc., 106, 4629-30 (1984), Fugita et al.
Chem. Pharm. Bull, 20, 539-42, Yamada, S.
J. Am. Chem. Soc., 106, 7861-67, Garigipati et al.
Tetrahedron Letters, 26, 1261-64 (1985), Hanessian, S. et al.
Chem. Lett., 671-4 (1985), Majaiyama et al.
J. Org. Chem., 48, 909-10 (1983), Fuganti et al.
Helv. Chim Acta, 47, 1101-13 (1964), Marxer et al.
J. Chem. Soc., Chem. Commun., 668-9 (1979), Takahashi et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Diastereocontrolled synthesis of 2-amino alcohols does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diastereocontrolled synthesis of 2-amino alcohols, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diastereocontrolled synthesis of 2-amino alcohols will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1321979

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.