Hybrid cell line for producing monoclonal antibody to a human T

Details Hybrid cell line for producing monoclonal antibody to a human T Hybrid cell line for producing monoclonal antibody to a human T

1984-08-29

1988-05-10

Tarcza, John E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

435 68, 4351722, 43524026, 436548, 424 85, C12P 2100, C12N 1500, A61K 39395, C07K 1504

Patent

active

047436816

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on essentially all normal human T cells and on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

REFERENCES:
patent: 4364937 (1982-12-01), Kung et al.

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