Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahyd

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436501, 546 79, 546108, 546110, G01N 3353, G01N 33566, C07D22106, C07D22112

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active

059255277

ABSTRACT:
The present invention relates to novel tricyclic tetrahydroquinoline compounds of the following formula, libraries containing such compounds, and to the generation of such combinatorial libraries composed of such compounds: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, n, and Y have the meanings provided.

REFERENCES:
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Grieco and Bahsas, "Role Reversal in the cyclocondensation of Cyclopentadiene with Heterodienophiles Derived from Aryl Amines and Aldehydes: Synthesis of Novel Tetrahydroquinolines." Tetrahedron Letters, 29 (46) :5855-5858 (1988).
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