Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-04-08
1988-05-10
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548337, A61K 31415, C07D23384
Patent
active
047436131
ABSTRACT:
Compounds having the formula: ##STR1## which are ester prodrugs of potent dopamine-.beta.-hydroxylase inhibitors and thus are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmeceutical compositions including these compounds, and methods of using these compounds to inhibit dopamine-.beta.-hydroxylase activity in mammals.
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Frazee James S.
Kaiser Carl
Kruse Lawrence I.
Ross Stephen T.
Briscoe Kurt G.
Fabiano Vincent L.
Jiles Henry R.
Lourie Alan D.
SmithKline Beckman Corporation
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