Treatment of vascular graft implants with G-CSF

Details Treatment of vascular graft implants with G-CSF Treatment of vascular graft implants with G-CSF

1997-09-19

1999-03-09

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, A61K 3818

Patent

active

058800905

ABSTRACT:
This invention provides methods for enhancing the endothelialization of synthetic vascular grafts by administering to a graft recipient an agent that mobilizes bone marrow-derived CD34.sup.+ cells into the bloodstream, that enhances the adherence to graft surfaces of blood-borne endothelial progenitors, or that stimulates the multiplication of endothelial progenitors that have adhered to the graft surfaces.

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