Pigmentation enhancer and method

Details Pigmentation enhancer and method Pigmentation enhancer and method

1994-05-31

1996-09-10

Dodson, Shelley A.

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

424 60, 424 63, A61K 742, A61K 740

Patent

active

055543596

ABSTRACT:
A composition comprising a lysosomotropic agent, and optionally phosphodiesterase inhibitors, and/or methylxanthines for increasing synthesis of melanin in a human melanocyte thereby enhancing pigmentation of the human skin. Use of this composition promotes tanning of the human skin and increases photoprotection from ultraviolet radiation. An organ culture system comprising viable human foreskin samples which may be used to test the effects of agents on human skin, including pigmentation enhancers on human skin.

REFERENCES:
patent: 3937809 (1976-02-01), Jacobi
patent: 4515773 (1985-05-01), Herlihy
patent: 4707354 (1987-11-01), Garlen et al.
patent: 4956489 (1990-09-01), Auriol et al.
patent: 4968497 (1990-11-01), Wolfram et al.
patent: 5273550 (1993-12-01), Prota
patent: 5279617 (1994-01-01), Prota et al.
patent: 5279618 (1994-01-01), Prota et al.
H. Saeki and A. Oikawa, "Stimulation of Tyrosinase Activity of Cultured Melanoma Cells by Lysosomotropic Agents", Journal of Cellular Physiology, 1983, 116:93-97.
M. Pathak, "Activation of the Melanocyte System by Ultraviolet Radiation and Cell Transformation", Annals New York Academy of Sciences, 1985, 453:328-339.
H. Saeki and A. Oikawa, "Stimulation by Ionophores of Tyrosinase Activity of Mouse Melanoma Cells in Culture", The Journal of Investigative Dermatology, 1985, 85:423-425.
Abstract of HCAPLUS, vol. 108:107130, [Abstract of WO 8704623 (Aug. 13, 1987)] Hruby et al.
Medline Abstract of J. of Cell Immunol, vol. 113(2), pp. 387-403, May 1988.
Biosis Abstract of Invest New Drugs vol. 6(4), 1988, pp. 251-258, Dorr et al.
HCAPLUS Abstract of WO9006104, Meybeck et al.
Medline Abstract of J. Biol. Chem, Mar. 15, 1986, Harper et al.
Medline Abstract of J. of Pigment Cell Res. 1987, pp. 44-50, Oikawa et al.
Biosis Abstract of J. Invest. Dermatology, vol. 89, 1987, pp. 269-273, Levine et al.
Biosis Abstract of Life Science, vol. 40(19), 1987 pp. 1889-1896, Hadley et al.
Derwent Abstract of Germany patent No. DE2,932,923, Feb. 19, 1981, Mausner.
Derwent Abstract of German patent No. DE3229738, Feb. 16, 1984, Cao et al.
Derwent Abstract of WO9107167, Sep. 28, 1993, Schering-Plough.
Derwent Abstract of Japanese patent No. 04182492, Jun. 30, 1992, Kao Corp.

Affiliated with

Also associated with

Rating

Pigmentation enhancer and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pigmentation enhancer and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pigmentation enhancer and method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1318682