Treating psychic disorders with piperidyl-indoles

Details Treating psychic disorders with piperidyl-indoles Treating psychic disorders with piperidyl-indoles

1977-08-01

1980-04-01

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

424263, 546201, 546273, A61K 31445, A61K 3144, C07D40104

Patent

active

041962095

ABSTRACT:
Novel piperidyl-indoles of the formula ##STR1## wherein X is selected from the group consisting of fluorine, chlorine and bromine when Y and Z are hydrogen or together form a double bond and X is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms when Y and Z form a double bond and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressant, antiemetic and antiparkinsonian activity and their preparations and novel intermediates therefore.

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Ungerstedt, Acta Physiol. Scand., 82, Supp. 367, pp. 69-93 (1971).
Malatray, J. et al., J. Pharmacol. (Paris), 1972, 3(3), 325-342.
Bergman, J., J. Heterocyclic Chem., 7, 1071-1076 (1970).

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