Substituted 5,11-dihydro-6H-dibenz[b,e]azepin-6-ones and pharmac

Details Substituted 5,11-dihydro-6H-dibenz[b,e]azepin-6-ones and pharmac Substituted 5,11-dihydro-6H-dibenz[b,e]azepin-6-ones and pharmac

1985-01-07

1986-01-28

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

2602393T, A61K 3155, C07D40312, C07D40314

Patent

active

045671788

ABSTRACT:
The invention relates to novel substituted 5,11-dihydro-6H-dibenz[b,e]azepin-6-one of the formula ##STR1## wherein A represents a (1-methyl-4-piperidinyl)-acetyl, (4-methyl-1-piperazinyl)-acetyl, or [(1-methyl-4-piperidinyl)-amino]-carbonyl group,
and the acid addition salts thereof, which have valuable pharmacological properties, particularly an ulcer-inhibiting and secretion-inhibiting activity. The compounds of Formula I may be prepared using methods conventionally used for analogous compounds.

REFERENCES:
patent: 4308207 (1981-12-01), Hunziker et al.
patent: 4336192 (1982-06-01), Steiner et al.
patent: 4447434 (1984-05-01), Trummlitz et al.
Chemical Abstracts, vol. 94, No. 19, May 11, 1981, 156722p.
Chemical Abstracts, vol. 95, No. 21, Nov. 23, 1981, 187040q.
Chemical Abstracts, vol. 91, No. 23, Dec. 3, 1979, 193150j.

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