Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-10-04
1980-08-26
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424251, 544238, 544333, 544405, C07D23924
Patent
active
042195535
ABSTRACT:
The compounds are C.sub.2 -C.sub.8 straight chain alkanes terminally substituted, symmetrically or unsymmetrically, by N-(N'-substituted guanidino), N-(N',N"-disubstituted guanidino), N-(N'-substituted thioureido), N-(nitromethylene amidino) or S-(N-substituted isothioureido)groups. Two compounds of the invention are 1,3-bis-[N'-(2-(3-methoxy-2-pyridylmethylthio)ethyl)guanidino]propane and 1-[N-(2-(3-methoxy-pyridylmethylthio)ethyl)guanidino]-3-[N'-2-(5-methyl-4- imidazolylmethylthio)ethyl)guanidino]propane. The compounds of this invention are inhibitors of H-2 histamine receptors.
REFERENCES:
patent: 3968227 (1976-07-01), Durant et al.
patent: 4070472 (1978-01-01), Durant et al.
patent: 4137319 (1979-01-01), Durant et al.
patent: 4139624 (1979-02-01), Durant et al.
Durant Graham J.
Ganellin Charon R.
Sach George S.
Edgerton William H.
Foggio Richard D.
Keps Joan S.
Rizzo Nicholas S.
Smith Kline & French Laboratories Limited
LandOfFree
Alkoxy pyridyl substituted alkanes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Alkoxy pyridyl substituted alkanes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkoxy pyridyl substituted alkanes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1305590