Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-03-24
1976-05-11
Gotts, Lewis
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D23930
Patent
active
039563014
ABSTRACT:
The process for brominating pyrimidine which comprises reacting bromine at an elevated temperature with the hydrogen halide addition salt of pyrimidine in an organic solvent substantially inert to the action of bromine under the conditions of the process. The process is also shown to be applicable to other nitrogen-containing heterocycles.
REFERENCES:
bredereck et al., Chem. Ber. 91 pp. 2832-2848 (1958).
Bredereck et al., Chem. Ber. 95, pp. 803-808 (1962).
Tetrahedron Letters, 22, pp. 2183-2186 (1972).
Gilman, et al., J. Am. Chem. Soc. 69, p. 1946 (1947).
Rec. Tran. Chem. 84 pp. 1101-1108 (1965).
J. Org. Chem. 27, pp. 1318-1323 (1962).
Eli Lilly and Company
Gotts Lewis
Morrison Dwight E.
Phillips D. R.
Smith Everet F.
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