N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas

Details N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas

1990-01-18

1992-10-13

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549406, 549399, 549407, 549404, 514459, 514507, 514457, 564 27, 564 29, 564 26, 564 48, 560313, A61K 3135, A61K 31215, C07D31104, C07C23900

Patent

active

051551276

ABSTRACT:
Novel N-[substituted aryl]-N'-(substituted alkoxy)-urea and thiourea derivatives are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful in preventing the intestinal absorption of cholesterol and thus are useful in the treatment of hypercholesterolemia and atherosclerosis.

REFERENCES:
patent: 4882353 (1989-11-01), Niewohner et al.

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