Process for preparing optically active (R)-(-)-3-halo-1,2-propan

Details Process for preparing optically active (R)-(-)-3-halo-1,2-propan Process for preparing optically active (R)-(-)-3-halo-1,2-propan

1990-04-19

1992-10-13

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435157, 435280, 4352521, 435843, C12P 718

Patent

active

051550300

ABSTRACT:
A process for preparing an optically active (R)-(-)-3-halo-1,2-propanediol comprising reacting an epihalohydrin with an epihalohydrin hydratase originating from a microorganism. For example, the microorganism belongs to the genus Corynebacterium or the genus Microbacterium. Epihalohydrins which can be used include epichlorohydrin and epibromohydrin. The reaction can be carried out at a temperature of from 5.degree. to 50.degree. C. and a pH of from 4 to 10.

REFERENCES:
patent: 4840907 (1989-06-01), Kasai et al.

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