Novel macrolactone derivatives and process of producing them

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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Other Related Categories

536 9, 26034341, C07H 1708, C07D31300

Type

Patent

Status

active

Patent number

042555647

Description

ABSTRACT:
By protecting the aldehyde group of a macrolide series antibiotics with a cyclic acetal or thioacetal, novel macrolide derivatives can be produced from the macrolide series antibiotics by releasing successively, the sugar moieties bonded to the macrolide antibiotics.
The novel marcolide derivatives obtained by this invention, that is, the derivatives of a macrolide series antibiotics produced by releasing partially or wholly the sugar moieties bonded are useful as intermediates for producing novel macrolide series antibiotics.

REFERENCES:
patent: 3923784 (1975-12-01), Kierstead et al.
patent: 3928387 (1975-12-01), Kierstead et al.
Omura, S., et al., J. Antibiotics, 27(2) 1974(147-149).

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