Process for producing 2-mercaptoethylamine hydrohalides

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564341, 564487, 564500, C07C14924

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045075000

ABSTRACT:
A process for producing 2-mercaptoethylamine hydrohalides of the general formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are identical or different, and each represents a hydrogen atom, a lower alkyl group, a hydroxy-substituted lower alkyl group or a phenyl group, and X represents a halogen atom,
which comprises reacting a 2-mercaptothiazoline of the general formula ##STR2## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined above, with a 2-halogenoethylamine hydrohalide of the general formula ##STR3## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and X are as defined above, in the presence of water.

REFERENCES:
Pavalova et al., "Chemical Abstracts", vol. 63, p. 18068a, (1965).
Clapp et al., "Journal Org. Chem.", vol. 26, pp. 1666-1668, (1961).
Gaul et al., "Journal Org. Chem.", vol. 25, pp. 869-871, (1960).
Johnston et al., "Journal Org. Chem.", vol. 29, pp. 2442-2444, (1964).

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