Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-04-24
1981-03-10
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544320, 546304, 546296, 546297, 546301, 546339, 546348, 548134, 548138, 548203, 548146, 548206, 548214, 548337, 548341, A61K 31505, C07D40114, C07D41714
Patent
active
042554284
ABSTRACT:
The compounds are substituted 2-amino-4-pyrimidones with a 5-(hydroxypyridylalkyl) substituent which are histamine H.sub.2 -antagonists. Two specific compounds are 2-[2-(3-bromo-2-pyridylmethylthio)ethylamino]-5-(2-hydroxy-4-pyridylmethyl )-4-pyrimidone and 2-[4-(3-methoxy-2-pyridyl)butylamino]-5-(2-hydroxy-4-pyridylmethyl)-4-pyri midone.
REFERENCES:
patent: 3980781 (1976-09-01), Snell et al.
patent: 4145546 (1979-03-01), Brown et al.
patent: 4153793 (1979-05-01), Durant et al.
patent: 4154834 (1979-05-01), Brown et al.
Brown Thomas H.
Durant Graham J.
Ganellin Charon R.
Daus Donald G.
Foggio Richard D.
Keps Joan S.
Lourie Alan D.
Smith Kline & French Laboratories Limited
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