Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1979-03-26
1981-11-17
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
544 22, 544021, 424246, 260239A, C07D50120
Patent
active
043012787
ABSTRACT:
7.beta.-Amino-3-cephem-3-cl-4-carboxylic acid compounds of the formula ##STR1## wherein R.sub.1.sup.a represents hydrogen or an amino protective group R.sub.1.sup.A and R.sub.1.sup.b represents hydrogen or an acyl group Ac, or R.sub.1.sup.a and R.sub.1.sup.b together represent a bivalent amino protective group, R.sub.2 represents hydroxyl or a radical R.sub.2.sup.A which together with the carbonyl grouping --C(.dbd.O)-- forms a protected carboxyl group and R.sub.3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides of 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R.sub.1.sup.a, R.sub.1.sup.b and R.sub.2.sup.A have the meanings mentioned under formula IA, R.sub.3.sup.o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products.
REFERENCES:
patent: 3840556 (1974-10-01), Kukulja
patent: 3860577 (1975-01-01), Kukulja
patent: 3989695 (1976-11-01), Scartazzini et al.
patent: 4007202 (1977-02-01), Verweij
patent: 4073902 (1978-02-01), Scartazzini et al.
patent: 4147864 (1979-04-01), Woodward et al.
Ferguson, Textbook of Organic Chemistry, pp. 248-253, (1965).
Chem. Communications 1971, p. 1137.
Tetrahedron Letters, No. 32, p. 3001, (1973).
J. Chem. Soc. Perkins Transactions I 1974 12, p. 1456.
Bickel Hans
Woodward Robert B.
Ciba-Geigy Corporation
Rabin Frederick H.
Rizzo Nicholas S.
LandOfFree
Process for the manufacture of enol derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the manufacture of enol derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the manufacture of enol derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1293465