Method of treating psychosis using tetrahydrocarbazole derivativ

Details Method of treating psychosis using tetrahydrocarbazole derivativ Method of treating psychosis using tetrahydrocarbazole derivativ

1986-01-15

1986-10-21

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514323, 514338, 514339, A61K 3144, A61K 31445

Patent

active

046186140

ABSTRACT:
Tetrahydrocarbazole derivatives of the general formula I ##STR1## in which Thc is a 1,2,3,4-tetrahydro-3-carbazolyl radical which can be substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, the two radicals Y are each H or together are a C--C bond, one radical Z is Ar and the other radical Z is H, A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- and Ar is a phenyl group which is unsubstituted or substituted once or twice by alkyl, O-alkyl, S-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, or is a 2- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts have effects on the central nervous system.

REFERENCES:
patent: 3634420 (1972-01-01), Littell et al.
patent: 3740404 (1973-06-01), Littell et al.
patent: 3752823 (1973-08-01), McManus

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