Murine hybridoma Lym-2 and diagnostic antibody produced thereby

Details Murine hybridoma Lym-2 and diagnostic antibody produced thereby Murine hybridoma Lym-2 and diagnostic antibody produced thereby

1985-05-24

1988-02-09

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530387, 435 7, 435 68, 4351722, 43524025, 935104, 935107, 935110, 424 11, 424 85, C12N 500, C07K 1504

Patent

active

047242124

ABSTRACT:
Hybridoma Lym-2 (ATCC No. HB 8613) produces murine IgGl monoclonal antibodies specifically against normal human B cells and derived malignancies. The Lym-2 antibodies have possible clinical utility for the in vivo diagnosis of human B-cell lymphomas and leukemias.

REFERENCES:
patent: 4513088 (1985-04-01), Levy et al.
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Marder, R. J. et al, Lab. Invest. 52(5):497-504 (1985), cited in Bio. Abstract 79086651.
Murray, L. J. et al, Clin. Exper. Immunol. 59(2):315-326 (1985), cited in Bio. Abstract 80005120.
Janossy, G. et al, Clin. Exper. Immunol. 59(2):257-266 (1985), cited in Bio. Abstract 80004036.
Jephthah, J. et al, Blood 63(2):319-325 (1984), cited in Bio. Abstract 78003585.
Winter, J. N. et al, Blood 63(1):140-146 (1984), cited in Bio. Abstract 78036670.
Delsol, G. et al, Ann. Pathol. 4(3):165-183 (1984), cited in Bio. Abstract 79031352.
Epstein, A. L. et al, J. Immunol. 133(2):1028-1036 (1984), cited in Bio. Abstract 78093014.
Gobbi, M. et al, Br. J. Haematol. 54(3):393-404 (1983), cited in Bio. Abstract 77028588.
Knowles, D. M. et al, Blood 62(1):191-199 (1983), cited in Bio. Abstract 77045013.

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