Use of OB-104 to treat ocular inflammation

Details Use of OB-104 to treat ocular inflammation Use of OB-104 to treat ocular inflammation

1991-12-03

1993-03-30

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514912, 424427, A61K 31425

Patent

active

051984547

ABSTRACT:
A novel compound for the treatment and prevention of ocular inflammation is disclosed. The compound, OB-104, is effective at both the early and late phases of inflammation.

REFERENCES:
patent: 3896223 (1975-07-01), Ariyan et al.
Remington Pharmaceutical Sciences, fifteenth edition (1975), pp. 1491-1492.
Polansky et al., "Anti-Inflammatory Agents: Steriods as Anti-Inflammatory Agents", Sears, Ed., Handbook of Experimental Pharmacology Springer-Verlag, (1985) 69:459-538.
Miyano et al., Opthalmic Res. (1984) 16:256-263.
Chiou et al., J. Ocular Pharmacol. (1985)1(4):383-389.
Bhattercherjee et al., "Effects of Lipooxygenase Products on Leukocyte Accumulation in the Rabbit Eye" Samuelsson et al., Eds., Leukorienes and Other Lipooxygenase Products Raven Press (1982) pp. 325-330.
Chang et al., J. Ocular Pharmacol. (1989) 5(4):353-360.

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