Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-03-14
1993-03-30
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514305, 540583, 546133, A61K 3155, A61K 3144, C07D22302, C07D45302
Patent
active
051984350
ABSTRACT:
The compounds of this invention are bicyclic, tricyclic, azabicyclic and azatricyclic amides represented by the formula: ##STR1## wherein: R.sub.1 and R.sub.2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a ##STR2## group wherein n, m and p are independently an integer of from 1 to 8 provided than n+m+p is equal to or less than 10; x is thio, sulfinyl or sulfonyl; Alk is straight or branched chain lower alkylene; R.sub.3 is selected from the group consisting of a bicycloalkylamino, tricycloalkylamino, azabicycloalkyl, azatricycloalkyl, azabicycloalkylamino, azatricycloalkylamino or dicycloalkylamino. The compounds are useful as anti-inflammatory and anti-allergy agents.
REFERENCES:
patent: 5019597 (1991-05-01), Mueller et al.
Deason James R.
Mueller Richard A.
Partis Richard A.
G. D. Searle & Co.
Kanady Mary Jo
Matukaitis Paul D.
Page Thurman K.
Venkat Jyothsna
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