Antimicrobial N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]-a

Details Antimicrobial N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]-a Antimicrobial N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]-a

1985-12-16

1989-06-13

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546304, C07D21374, A61K 3144

Patent

active

048393720

ABSTRACT:
N-[1-alkyl or arylmethyl)-4(1H)-pyridinylidine]-alkanamine and pharmaceutically acceptable acid addition salts thereof, for example, N-(1-octyl-4(1H)-pyridinylidine)-octanamine monohydrochloride salt, which are useful as antimicrobial agents, especially on living tissues and nonliving surfaces and most especially against pathogenic dental microbes, and a process for perparation, methods of use and compositions thereof are disclosed.

REFERENCES:
patent: 4206215 (1980-06-01), Bailey
patent: 4598082 (1986-07-01), Bailey
Landquist, Jounral of the Chemical Society, Perkin Transactions I, No. 4, pp. 454-456, 1976.
Merck Index, 9th Edition, (1976), p. 254.

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