Methylthioquinolyl guanidine derivative, process of preparation

Details Methylthioquinolyl guanidine derivative, process of preparation Methylthioquinolyl guanidine derivative, process of preparation

1988-02-23

1989-06-13

Sutto, Anton H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546157, 546168, 546169, 546170, A61K 3147, C07D40112

Patent

active

048393665

ABSTRACT:
The compound of formula (I): ##STR1## N-cyclohexyl-N"-4-(2-methylthioquinolyl)-N'-2-thiazolyl-guanidine and pharmaceutically acceptable salts thereof is a valuable antiinflammatory, analgesic and antipyretic agent.
The compound of the invention may be formulated with conventional pharmaceutically acceptable carriers or diluents to provide a pharmaceutical composition.

REFERENCES:
patent: 4293549 (1981-10-01), Rachlin et al.
patent: 4680300 (1987-07-01), Nelson et al.
Burger, "Medicinal Chemistry", Interscience Publishers, N.Y. (2nd Ed.), p. 75 (1960).
Labrecque et al., Pharmacology, pp. 169-174 (1982).

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