Cough/cold mixtures comprising non-steroidal anti-inflammatory d

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514420, 514568, 514576, A61K 3127, A61K 3134, A61K 3140, A61K 3154

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active

048393541

ABSTRACT:
Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an anti-histamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.

REFERENCES:
patent: 4230717 (1980-10-01), Brown et al.
patent: 4279906 (1981-07-01), Frosch et al.
patent: 4322427 (1982-03-01), Buyniski et al.
Chem. Abst. (91)-117518v (1979), (97)-156155t (1982) and 90-207052h (1983).
"Non-Steroidal Anti-Inflammatory Drugs if Combined With Anti-Histamine and Anti-Serotonin Agents Interfere with the Bronchial and Platelet Effects of Platelet-Activating Factor" (PAF-Acether), Eur. J. Pharmacol., vol. 82, pp. 121-130 (1982).
Unlisted Drugs, vol. 20, No. 11, Nov. 1968, p. 169n, "Sinubid".
Unlisted Drugs, vol. 23, No. 3, Mar. 1971, p. 36, "Co-Tylenol".
Traber, Daniel L., "Ibuprofen and Diphenhydramine Reduce the Lung Lesion of Endotoxemia in Sheep", J. Trauma, 1984, 24(9), 835-40.

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