Prostaglandin compounds

Details Prostaglandin compounds Prostaglandin compounds

1974-02-27

1976-06-29

Gersil, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260210R, 260246R, 2603433R, 2603457, 2603462R, 2603473, 260408R, 2605011, 26050117, 260514D, 260617R, 424305, 424317, C07C 6138, C07C 6974

Patent

active

039667928

ABSTRACT:
New prostaglandin analogues having therapeutic utility of the formula: ##SPC1##
(wherein B is a grouping of the formula: ##SPC2##
X is --CH.sub.2 CH.sub.2 -- or cis --CH=CH--, Y is trans --CH=CH-- or, when X is --CH.sub.2 CH.sub.2 --, Y is additionally --CH.sub.2 CH.sub.2 --, A is alkyl of 1 through 3 carbon atoms, n is 4 or 5, and indicates attachment of the hydroxy radical to the carbon atom in alpha or beta configuration), and alkyl esters thereof, and cyclodextrin clathrates of such acids and esters, and non-toxic salts of such acids.

REFERENCES:
patent: 3843713 (1974-10-01), Finch et al.

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