Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivative

Details Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivative Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivative

1974-09-09

1976-06-29

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260286R, 260471A, 424258, C07D21556

Patent

active

039667430

ABSTRACT:
Cycloalkano-quinolone derivatives having anti-microbial activity characterized by the formula: ##SPC1##
Wherein one of R.sub.1 and R.sub.2 designates hydrogen, halogen, nitro, amino, hydroxyl, acylamino, acyloxy, alkoxy or aryloxy and the other taken together with R.sub.3 forms an akylene bridge containing 2 to 6 carbon atoms, X is hydrogen, lower alkyl, which may be substituted by a member of the group consisting of halogen, hydroxyl, acyloxy, alkoxy, aryloxy, aralkyloxy, mercapto, alkylmercapto, arylmercapto, arylsulfonyl, and alkylsulfonyl, or X is unsubstituted alkenyl including alkadienyl, or alkynyl and Y is hydroxyl, amino or lower alkoxy, and the pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 2966489 (1960-12-01), Hepworth et al.
patent: 3287458 (1968-11-01), Kaminsky et al.
patent: 3324135 (1967-06-01), Lesher
patent: 3506667 (1970-04-01), Kaminsky
patent: 3524858 (1970-08-01), Kaminsky et al.

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