Andrexiant aminopiperidines intermediates thereto and drugs cont

Details Andrexiant aminopiperidines intermediates thereto and drugs cont Andrexiant aminopiperidines intermediates thereto and drugs cont

1981-12-03

1983-10-11

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546193, 546194, 546244, A61K 31445, C07D40104

Patent

active

044092288

ABSTRACT:
The present invention relates to novel 4-amino-1-(2-pyridyl)piperidines with anorexiant action, of formula: ##STR1## in which R represents hydrogen, a halogen, a methyl group, a trifluoromethyl group, a lower alkoxy group, a trifluoromethoxy group, a 2,2,2-trifluoroethoxy group, a lower alkylthio group, a trifluoromethylthio group, a possibly substituted phenoxy group or a possibly substituted phenylthio group; to salts thereof; to a process for preparation thereof; to drugs containing same; and to intermediate products in the synthesis thereof.

REFERENCES:
Schatz, V. In Medicinal Chemistry, 2nd Ed. (Burger, Editor), Interscience, New York, 1960, pp. 78-79.
Stern, P., Arch. Exp. Pathol. Pharmacol., 1942, 199, 251-264.
Cerkovnikov, E., et al., Chem. Ber., 1941, 74, 1648-1657.

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