Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1976-06-02
1978-02-21
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602948C, A61K 3154, C07D41704
Patent
active
040753409
ABSTRACT:
This invention relates to derivatives having the formula: ##STR1## in which R.sub.1 is hydrogen or alkyl having 1-6 carbon atoms; X is (CHR.sub.2).sub.m in which m is an integer from 2 to 15, or (CHR.sub.2).sub.n R.sub.3 in which n is an integer from 1 to 15, R.sub.2 is hydrogen, or a hydroxy, acyloxy or alkyl group having 1-6 carbon atoms, and the various symbols R.sub.2 may have different meanings in each radical (CHR.sub.2) when several radicals (CHR.sub.2) are present, R.sub.3 is a trichloromethyl, acetyl, carboxy or alkoxycarbonyl group, or a phenyl, phenoxy, benzoyl, thienyl or pyridyl radical optionally substituted with at least a halogen atom, or a hydroxy, nitro, amino, cyano, carboxy, alkyloxycarbonyl, alkyl having 1-6 carbon atoms, alkoxy having 1-6 carbon atoms or methylenedioxy group, and to the acid addition salts of the derivatives of the formula (I).
Said derivatives have useful anti-inflammatory and anti-arrhythmic activities and an inhibiting action on blood platelet aggregation.
REFERENCES:
karrer, Organic Chemistry, 4th Eng. Edition, Elsevier Pub. Co., (N.Y.), p. 928, 1950.
Chemical & Engineering News, vol. 50 p. 18, Apr. 3, 1972.
Burger, Medicinal Chemistry, Sec. Edition, p. 497, 1960.
Elderfield, Heterocyclic Compounds, vol. I, Wiley Pub., p. 485, (1950).
Klingsberg, Pyridine and its Derivatives, Part Two, Interscience Pub., pp. 50-51, (1961).
Descamps et al., Chem. Abstracts, vol. 59, (2), pp. 1605-1607, July 22, 1963.
Parcor
Rotman Alan L.
LandOfFree
Thieno [2,3-C] pyridine derivatives and therapeutic composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Thieno [2,3-C] pyridine derivatives and therapeutic composition , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thieno [2,3-C] pyridine derivatives and therapeutic composition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-126813