Treatment of multi-drug resistant tumors with quinolyl-and isoqu

Details Treatment of multi-drug resistant tumors with quinolyl-and isoqu Treatment of multi-drug resistant tumors with quinolyl-and isoqu

1992-03-13

1993-03-02

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514307, A61K 3147

Patent

active

051909570

ABSTRACT:
This invention relates to quinolyloxazole-2-ones which are useful in the treatment of multi-drug resistant tumors. The quinoloyloxazole-2-ones act to prevent drug resistance and thus allow conventional chemotherapeutic agents to kill tumor cells as if drug resistance were not present.

REFERENCES:
patent: 4886811 (1989-12-01), Jones et al.
patent: 4990519 (1991-02-01), Jones et al.

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