Kluyveromyces as a host strain

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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435255, 435256, 435320, 435 91, 935 28, 935 37, 935 56, C12N 1500, C12N 120, C12N 500

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049435299

ABSTRACT:
Kluyveromyces hosts and DNA expression cassettes for use in Kluyveromyces are provided for transcription of endogenous and/or exogenous DNA, and production of peptides, for enhancing production of an endogenous product, or producing an exogenous product. The Kluyveromyces hosts find particular use for secretion of a desired peptide product, where signal sequences may be native to the peptide or provided from endogenous or exogenous signal sequences, including synthetic sequences, functional in Kluyveromyces. A transformation procedure is provided for efficiently transforming Kluyveromyces.

REFERENCES:
Ito et al. (1983) J. Bacteriology 153: pp. 163-168.

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