Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Patent
1980-04-25
1982-04-20
Ives, P.
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
428407, 428500, 521 56, 2601125R, 260117, 260 8, 424 8, 424 85, 424 88, 424 12, 25230135, 525 541, 526268, B32B 516, B32B 904, G01N 3100, G01N 3300
Patent
active
043260080
ABSTRACT:
Highly fluorescent, stable and biocompatible microspheres are obtained by copolymerizing an acrylic monomer containing a covalent bonding group such as hydroxyl, amine or carboxyl, for example, hydroxyethylmethacrylate, with an addition polymerizable fluorescent comonomer such as dansyl allyl amine. A lectin or antibody is bound to the covalent site to provide cell specificity. When the microspheres are added to a cell suspension the marked microspheres will specifically label a cell membrane by binding to a specific receptor site thereon. The labeled membrane can then be detected by fluorescence of the fluorescent monomer.
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California Institute of Technology
Ives P.
Jacobs Marvin E.
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