Process for producing antibiotic streptovaricin

Details Process for producing antibiotic streptovaricin Process for producing antibiotic streptovaricin

1992-01-27

1993-03-02

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435124, 4352535, 435262, 435267, 435886, 435803, 540456, 540461, C12R 1465, C12P 1718, C12P 1708, C07E 1700

Patent

active

051908662

ABSTRACT:
A method for separation and recovery of polymeric beads from an antibiotic fermentation broth comprising suspending a mixture of the beads and any inherent mold from the fermentation in an aqueous solution having a specific gravity which is effective to cause the beads to form a discrete layer at or on the surface of the solution, separate and apart from the mold. The separate layer of the beads may then be easily removed from the liquid by a conventional physical methods.

REFERENCES:
patent: 3116202 (1963-12-01), Dietz et al.
patent: 3846400 (1974-11-01), Umezawa et al.
patent: 4656143 (1987-04-01), Baker et al.
patent: 4659660 (1987-04-01), Hamill et al.
patent: 4962047 (1990-10-01), Place
Reinhart et al., "Biochemistry" vol. 13 #5 pp. 861-867 (1974).
Sasaki et al., "J. Antibiotics" vol. 29 #2 pp. 147-154 (Feb. 1976).
Onodera et al., "J. Antibiotics" vol. 32 #5 pp. 545-547 (May 1979).
Wang "Annual N.Y. Academy Sciences" 431, pp. 313-321 (1983).

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