High purity process for the preparation of 4,6-diamino-1,3-benze

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564443, 568709, 568711, 568712, 568713, 568933, C07C21300

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active

RE0347450

ABSTRACT:
High purity 4,6-dinitro-1,3-benzenediol is prepared by (a) contacting a 1,2,3-trihalobenzene with a nitrating agent and an acid under reaction conditions such that a 1,2,3-trihalo-4,6-dinitrobenzene is produced, (b) contacting the 1,2,3-trihalo-4,6-dinitrobenzene prepared in (a) with an alkanol and a base under reaction conditions such that as 4,6-dinitro-2-halo-1,3-benzendiol is produced, and (c) contacting the 4,6-dinitro-2-halo-1,3-benzenediol prepared in (b) with a hydrogenating agent in the presence of a solvent and a catalyst under reaction conditions such that a 4,6-diamino-1,3-benzendiol is produced. This 4,6-diamino-1,3-benzene diol is useful in the preparation of high molecular weight polybenzoxazoles.

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Wolfe et al, Macromolecules, vol. 14, No. 4, pp. 909-914, 1981.

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