Triaromatic compounds and pharmaceutical/cosmetic compositions c

Details Triaromatic compounds and pharmaceutical/cosmetic compositions c Triaromatic compounds and pharmaceutical/cosmetic compositions c

1998-05-26

2000-11-21

Lambkin, Deborah C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514544, 514617, 514277, 514356, 514354, 514438, 514448, 514700, 514730, 514733, 5142375, 568425, 568744, 568807, 564161, 564182, 549 71, 549 79, 546322, 546326, 546342, 560102, 544175, A61K 3119, A61K 31325, A61K 31165, A61K 31435, A61K 3144, A61K 3138, C07C 3334, C07C23300, C07D26530

Patent

active

061504130

ABSTRACT:
Novel pharmaceutically/cosmetically-active triaromatic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

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Jong, L. et al; Conformational effects on retinoid receptor selectivity. Effect of 9-double bond geometry . . . , vol. 36, No. 18, 1993, pp. 2605-2613.
Kegechika, H. etc.; Retinobenzoic acids. Structure-activity relationships . . . Journal of medicinal Chemistry, vol. 31, No. 11, 1988, pp. 2182-2192.
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