Process for preparing substituted 2,4-diaminopyrimidines and iso

Details Process for preparing substituted 2,4-diaminopyrimidines and iso Process for preparing substituted 2,4-diaminopyrimidines and iso

1977-02-07

1978-02-21

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260307H, C07D23948, C07D26108

Patent

active

040752097

ABSTRACT:
A process for the preparation of 2,4-diamino-5-benzylpyrimidines by reacting 4-bromomethylisoxazole with an aromatic compound of the formula ##STR1## wherein R, R.sub.1 and R.sub.2 are hydrogen, lower alkoxy and lower alkyl, AND SUBSEQUENTLY TREATING THE REACTION PRODUCT WITH A GUANIDINE SALT, IS DESCRIBED.

REFERENCES:
patent: 3629474 (1971-12-01), Ghosh et al.
patent: 3850962 (1974-11-01), Grunberg et al.
patent: 3956327 (1976-05-01), Gresswell et al.
J. P. Tarsio et al., Jr. Org. Chem., 22, 192-193.

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