Use of an osmolyte for reducing or abolishing no-covalent intera

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 912, 435 71, 435 72, 435 792, C12Q 168, G01N 3353, G01N 33567, G01N 33537

Patent

active

061500941

ABSTRACT:
The present invention relates to the use of an osmolyte for reducing or abolishing non-covalent interactions of biological molecules to inert surfaces. Furthermore, the present invention relates to kits that may be employed for uses in accordance with the present invention.

REFERENCES:
patent: 5181999 (1993-01-01), Wiktorowicz
patent: 5587128 (1996-12-01), Wilding et al.
Moncef Zouali, et al., "A Rapid ELISA For Measurement of Antibodies to Nucleic Acid Antigens Using UV-treated Polystyrene Microplates," Journal of Immunological Methods, 90:105-110 (1986).
Thakar, M., et al., "Osmolyte Mediation of T7 DNA Polymerase and Plasmid DNA Stability," Biochemistry 33: 12255-12259 (1994).

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