Process of producing phosphatidylcholine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...

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554 80, C07F 902

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053211456

ABSTRACT:
A process of producing phosphatidylcholine derivatives by the reaction of glycerophosphatidylcholine with at least one fatty acid anhydride in the presence of a pyridine catalyst is described. The reaction is carried out in a melt of the glycerophosphatidylcholine, the at least one fatty acid anhydride and the catalyst.

REFERENCES:
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patent: 4690784 (1987-09-01), Nanba
Kobayashi et al., Journal of Jap. Med. Soc. Biol. Interface, vol. 21 No. 1/2, pp. 104-110 (1990) (Abstract).
E. Baer et al., "Synthesis of Saturated . . . Glycerylphophorylcholine", Can. J. Biochem. Physiol. 37, pp. 953-959 (1959).
K. Patel et al., "A conveient Synthesis . . . 4-pyrrolidinopyridine", J. Lipid Research, vo-. 20, 1979, pp. 674-677.
50th Anniversary of Phospholipid Research (EPL) edited by K. Gunerdmann et al., Int'l Symposiu, Dec. 1989, Cologne, wbn-Verlag.Bingen/Rhein, 1990.
Patent Abstract of J61275287-A (JP), Dec. 5, 1986.

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